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The CellMaker PLUSTM system and the HybridBag have been designed to enable you to culture any cell type with full control of dissolved oxygen and carbon dioxide concentration with pH monitoring and control (optional). In recent years there has been a significant increase in the demand for mammalian cell culture procedures in the development and production of biopharmaceuticals. Our studies have shown that the control of dO2 is essential to achieve optimal cell concentrations and viabilities for mammalian and insect cells. Too little oxygen and cells do not achieve the concentrations required for seeding large-scale bioreactors. Too much oxygen and the cells undergo apoptosis. The culture of E. coli and Pichia are very straightforward and can be performed without the need for automated dO2 or pH control. They just need plenty of oxygen and the CellMaker PLUS with the CellexusBag can achieve oxygen mass transfer rates similar to a stirred bioreactor and considerably greater than a shaker flask2. If you need a disposable bioreactor that can culture just about any cell type, the CellMaker PLUS is the simple choice. The CellMaker PLUS is a fully automated system. Read more. If you would like to arrange a demonstration at an exhibition near you, please contact us.
*Patented and patents pending |
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incorporates a series of new technologies and will be available immediately in two size ranges: 1-8 litres and 10-50 litres. |
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Cellexus Limited Cellexus Limited is a company incorporated under English law. Company registration number: 06513741 VAT number: TBA Registered Office: Cellexus House 12 Ramsay Court, Hinchingbrooke Business Park, Huntingdon, Cambridgeshire PE29 6FY United Kingdom. info@cellexusbiosystems.com |
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Down load Simple batch and fed-batch strategies for CHO-S cells |
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Down load CellMaker PLUS brochure |
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The CellMaker PLUS |
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a single-use bioreactor which has been designed to solve the challenges associated with culturing mammalian and insect cells in a single-use format. |
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The CellMaker PLUS |
